| 发明名称 |
MEASURING CIRCULATING THERAPEUTIC ANTIBODY, ANTIGEN AND ANTIGEN/ANTIBODY COMPLEXES USING ELISA ASSAYS |
| 摘要 |
The present invention relates to a method of determining the efficacy of an antibody immunotherapy in a patient, the method comprising the step of detecting the level of circulating anti-CD52/CD52 complexes in a sample obtained from the patient previously, wherein the level of circulating anti-CD52/CD52 complexes is indicative of a reduction in the amount of therapeutic antibody reaching the target cells. |
| 申请公布号 |
EP1438583(B1) |
申请公布日期 |
2009.09.16 |
| 申请号 |
EP20020761799 |
申请日期 |
2002.09.20 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
ALBITAR, MAHER;KEATING, MICHAEL, J.;MANSHOURI, TAGHI |
| 分类号 |
G01N33/53;G01N33/564;A61K39/395;A61P5/14;A61P13/08;A61P13/10;A61P19/02;A61P25/00;A61P27/02;A61P35/00;A61P35/02;A61P37/02;A61P37/06;G01N33/543;G01N33/574;G01N33/577 |
主分类号 |
G01N33/53 |
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