| 发明名称 |
METALLOPROTEASE INHIBITORS CONTAINING A HETEROCYCLIC MOIETY. |
| 摘要 |
<p>The present invention relates generally..to heterocyclic metalloprotease inhibiting compounds of formula (I). More particularly, the present invention provides a new class of heterocyclic MMP 3, MMP 8 and/or MMP 13 inhibiting compounds with a squaramide or benzoxazinone moiety, that exhibit an increased potency and selectivity in relation to currently known MMP 13, MMP 8 and MMP 3 inhibitors.</p> |
| 申请公布号 |
MX2009009540(A) |
申请公布日期 |
2009.09.16 |
| 申请号 |
MX20090009540 |
申请日期 |
2008.03.07 |
| 申请人 |
ALANTOS PHARMACEUTICALS HOLDING, INC. |
发明人 |
CHRISTIAN GEGE;CARINE CHEVRIER;ARTHUR TAVERAS;BRIAN M. GALLAGHER JR. |
| 分类号 |
C07D217/04;A61K31/538;C07D239/88;C07D401/12;C07D401/14;C07D403/12;C07D405/14;C07D409/12;C07D413/12;C07D413/14;C07D417/12;C07D471/02;C07D495/02;C07D495/20;C07D498/02 |
主分类号 |
C07D217/04 |
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