发明名称 |
VERFAHREN ZUR AUFREINIGUNG VON ROPINIROLHYDROCHLORID |
摘要 |
<p>The present invention provides an improved process for the purification of ropinirole hydrochloride. The process includes (i) treating ropinirole hydrochloride with sodium dithionate and charcoal in suitable alcoholic solvent; (ii) triturating the ropinirole hydrochloride obtained in step (i) with ethanol; (iii) reacting the triturated solid with base in water immiscible solvent and isolating the free base; and (iv) treating the free base obtained in step (iii) with ethanolic HCl to give ropinirole hydrochloride.</p> |
申请公布号 |
AT442357(T) |
申请公布日期 |
2009.09.15 |
申请号 |
AT20070736577T |
申请日期 |
2007.03.21 |
申请人 |
ALEMBIC LIMITED |
发明人 |
DESHPANDE, PANDURANG;LUTHRA, PARVEN;ACHARYA, HITARTH |
分类号 |
C07D209/34 |
主分类号 |
C07D209/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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