发明名称 2-AMINOQUINOLINES
摘要 <p>The present invention relates to compounds of the general formula (I) wherein A, R1, R2, R3, R4, and R5 are as described herein and the use thereof as 5-HT5A receptor antagonists, theirmanufacture, pharmaceutical compositions containing them and their use as medicaments. The compounds of the general formula (I) are useful in the prevention and/or treatment of depression, anxiety disorders, schizophrenia, panic disorders, agoraphobia, social phobia, obsessive compulsive disorders, post-traumatic stress disorders, pain, memory disorders, dementia, disorders of eating behaviors, sexual dysfunction, sleep disorders, abuse of drugs, motor disorders such as Parkinson's disease, psychiatric disorders or gastrointestinal disorders.</p>
申请公布号 WO2009109502(A1) 申请公布日期 2009.09.11
申请号 WO2009EP52253 申请日期 2009.02.26
申请人 F. HOFFMANN-LA ROCHE AG;KOLCZEWSKI, SABINE;RIEMER, CLAUS;ROCHE, OLIVIER;STEWARD, LUCINDA;WICHMANN, JUERGEN;WOLTERING, THOMAS 发明人 KOLCZEWSKI, SABINE;RIEMER, CLAUS;ROCHE, OLIVIER;STEWARD, LUCINDA;WICHMANN, JUERGEN;WOLTERING, THOMAS
分类号 A61P25/00;A61K31/47;A61K31/4709;C07D215/38;C07D401/04;C07D405/12;C07D405/14;C07D413/04 主分类号 A61P25/00
代理机构 代理人
主权项
地址