摘要 |
<p>The present invention relates to compounds of the general formula (I) wherein A, R1, R2, R3, R4, and R5 are as described herein and the use thereof as 5-HT5A receptor antagonists, theirmanufacture, pharmaceutical compositions containing them and their use as medicaments. The compounds of the general formula (I) are useful in the prevention and/or treatment of depression, anxiety disorders, schizophrenia, panic disorders, agoraphobia, social phobia, obsessive compulsive disorders, post-traumatic stress disorders, pain, memory disorders, dementia, disorders of eating behaviors, sexual dysfunction, sleep disorders, abuse of drugs, motor disorders such as Parkinson's disease, psychiatric disorders or gastrointestinal disorders.</p> |
申请人 |
F. HOFFMANN-LA ROCHE AG;KOLCZEWSKI, SABINE;RIEMER, CLAUS;ROCHE, OLIVIER;STEWARD, LUCINDA;WICHMANN, JUERGEN;WOLTERING, THOMAS |
发明人 |
KOLCZEWSKI, SABINE;RIEMER, CLAUS;ROCHE, OLIVIER;STEWARD, LUCINDA;WICHMANN, JUERGEN;WOLTERING, THOMAS |