发明名称 |
METHOD OF ASSESSING MAMMALIAN EMBRYO QUALITY |
摘要 |
A method of assessing the health of each oocyte or embryo of a mammal from a plurality of oocytes/embryos of the mammal is provided. The method comprises the steps of: measuring gap junctional coupling strength or connexin43 expression of follicular cells associated with each oocyte; and identifying the gap junctional coupling strength/connexin43 expression of follicular cells associated with each oocyte, wherein the greater the coupling strength/connexin43 expression of follicular cells associated with an oocyte relative to the coupling strength/connexin43 expression of follicular cells associated with each other oocyte, the healthier the oocyte and the embryo resulting from that oocyte. Kits for conducting these methods are also provided.
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申请公布号 |
CA2717483(A1) |
申请公布日期 |
2009.09.11 |
申请号 |
CA20092717483 |
申请日期 |
2009.03.05 |
申请人 |
THE UNIVERSITY OF WESTERN ONTARIO |
发明人 |
KIDDER, GERALD M.;WANG, HONG-XING;TONG, DAN;TEKPETEY, FRANCIS R. |
分类号 |
C12Q1/02;A61B5/053;C12Q1/00;G01N33/52;G01N33/53;G01N33/543;G01N33/68 |
主分类号 |
C12Q1/02 |
代理机构 |
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主权项 |
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地址 |
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