发明名称 CXCR2 INHIBITORS
摘要 The invention relates to compounds of the formula I in which R1, R2, X, A, B, Z and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.
申请公布号 US2009227625(A1) 申请公布日期 2009.09.10
申请号 US20080337040 申请日期 2008.12.17
申请人 SANOFI-AVENTIS 发明人 HACHTEL STEPHANIE;DEDIO JUERGEN;DEFOSSA ELISABETH;GRUENEBERG SVEN;HEITSCH HOLGER;BOCK WILLIAM;CHEN CHARLIE;KOSLEY RAYMOND;KUNG CHUNG-YI;PATEK MARCEL;SHER ROSY;SHIMSHOCK STEPHEN;WEICHSEL ALEKSANDRA
分类号 A61K31/47;A61K31/192;A61K31/38;A61P29/00;C07C229/34;C07D215/48;C07D333/70 主分类号 A61K31/47
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