发明名称 DERIVATIVES OF N-(1,5-DIPHELYL-1H-PYRAZOL-3-YL)SULPHONAMIDE WITH AFFINITY TO CB1 RECEPTORS
摘要 FIELD: chemistry. ^ SUBSTANCE: present invention refers to compounds of general formula (I) in the state of base salt or acid-addition salt, to method of their preparation and to the pharmaceutical composition thereof In the said formula R1 is (C1-C6)alkyl; (C3-C7)cycloalkyl unsubstituted or substituted once or more than once; (C3-C7)cycloalkylmethyl unsubstituted or substituted once or more than once; phenyl unsubstituted or substituted ; benzyl unsubstituted or substituted once or twice ; thienyl unsubstituted or substituted ; R2 is atom hydrogen or (C1-C3)alkyl; R3 is (C1-C5)alkyl; R4, R5, R6, R7, each R8 and R9 independently represents the atom of hydrogen, atom of halogen, (C1-C7)alkyl, (C1-C5)alkoxy or trifluoromethyl radical; n is 0, 1 or 2; Alk is (C1-C4)alkyl. ^ EFFECT: new compounds possess useful biological activity. ^ 5 cl, 5 tbl, 4 ex
申请公布号 RU2366657(C2) 申请公布日期 2009.09.10
申请号 RU20060129297 申请日期 2005.01.07
申请人 SANOFI-AVENTIS 发明人 BART FRANSIS;KONZHI KRISTIAN;MARTINES SERZH;RINAL'DI-KARMONA MJURIEHLL'
分类号 A61K31/415;A61K31/4155;A61P1/00;A61P25/00;A61P29/00;A61P37/00;C07D231/12;C07D409/12;C07D413/14 主分类号 A61K31/415
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