发明名称 Novel Pharmaceutical Compounds
摘要 The instant invention provides compounds of Formula (Ia) which are leukotriene biosynthesis inhibitors, wherein X is O or S, Y is O, S, -NR6-CHR7- or -NR8-C(O)- and A is selected from 5-membered aromatic heterocyclic ring, 6-membered aromatic heterocyclic ring, naphthelenic or heterobicyclic aromatic ring system, phenyl and benzyl. A is optionally mono- or disubstituted. Compounds of Formula (Ia) are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
申请公布号 US2009227638(A1) 申请公布日期 2009.09.10
申请号 US20060886757 申请日期 2006.03.21
申请人 BLOUIN MARC;GRIMM ERICH L;GAREAU YVES;GAGNON MARC;JUTEAU HELENE;LALIBERTE SEBASTIEN;MACKAY BRUCE;FRIESEN RICHARD 发明人 BLOUIN MARC;GRIMM ERICH L.;GAREAU YVES;GAGNON MARC;JUTEAU HELENE;LALIBERTE SEBASTIEN;MACKAY BRUCE;FRIESEN RICHARD
分类号 A61K31/433;A61K31/4245;A61P9/10;C07D417/12;C07D417/14 主分类号 A61K31/433
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