发明名称 |
GLP-1 gene delivery for the treatment of type 2 diabetes |
摘要 |
This patent discloses compositions and methods of use thereof to normalize the blood glucose levels of patients with type 2 diabetes. It relates particularly to a plasmid comprising a chicken beta actin promoter and enhancer; a modified GLP-1 (7-37) cDNA (pbetaGLP1), carrying a furin cleavage site, which is constructed and delivered into a cell for the expression of active GLP-1.
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申请公布号 |
US2009227660(A1) |
申请公布日期 |
2009.09.10 |
申请号 |
US20080074865 |
申请日期 |
2008.03.05 |
申请人 |
OH SEUNGJOON;LEE MINHYUNG;KO KYUNGSOO |
发明人 |
OH SEUNGJOON;LEE MINHYUNG;KO KYUNGSOO |
分类号 |
A61K48/00;A61K38/00;A61K47/48;C07K14/605 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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