发明名称 |
Oxazole and thiazole compounds as beta-catenin modulators and uses thereof |
摘要 |
A series of oxazole and thiazole compounds are shown herein to be small molecule inhibitors of the Wnt pathway that specifically target the activity of the stabilized pool of beta-cat oxazole and thiazole compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, cancer, and others.
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申请公布号 |
US2009227624(A1) |
申请公布日期 |
2009.09.10 |
申请号 |
US20090322070 |
申请日期 |
2009.01.28 |
申请人 |
DASGUPTA RAMANUJ;GONSALVES FOSTER |
发明人 |
DASGUPTA RAMANUJ;GONSALVES FOSTER |
分类号 |
A61K31/4725;A61K31/421;A61K31/426 |
主分类号 |
A61K31/4725 |
代理机构 |
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代理人 |
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地址 |
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