发明名称 |
MODULATION OF RHAMM (CD168) FOR SELECTIVE ADIPOSE TISSUE DEVELOPMENT |
摘要 |
<p>Herein is described the methods and compositions for modulation of Rhamm, also known as CD186, and its effects on wound repair, muscle differentiation, bone density and adipogeneisis through its ability to regulate mesenchymal stem cell differentiation. Compositions and methods are provided for blocking Rhamm function for selectively increasing subcutaneous, but not, visceral fat. Compositions and methods for modulating Rhamm in wound repair are also described.</p> |
申请公布号 |
EP2097092(A2) |
申请公布日期 |
2009.09.09 |
申请号 |
EP20070874313 |
申请日期 |
2007.11.21 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;LAWSON HEALTH RESEARCH INSTITUTE |
发明人 |
TURLEY, EVA, A.;BISSELL, MINA, J. |
分类号 |
A61K38/00;C12N5/077 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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