DETECTION OF ANTIBODIES TO GANGLIOSIDES USING SOLID-PHASE REACTANTS COATED WITH CARBONYL GROUPS

摘要

Method of detecting antibodies to one or more ganglioside(s) of interest in a sample are disclosed which comprise using a solid-phase reactant having carbonyl groups attached thereon, and th e ganglioside(s) of interest linked to the solid-phase reactant by an amide bond between an amino group of ganglioside of interest and a carbonyl group attached to the solid-phase reactant. The methods of detecting antibodies to ganglioside(s) of interest can be used in methods of diagnosing neuropathies in an individual.