| 摘要 |
The present invention concerns novel compounds of formula (I), a N-oxide for m, a pharmaceutically acceptable acid addition salt or a stereochemically isomeric form thereof, wherein n is zero, 1, 2 or 3; X is N or CH; each R1 independently is halo, nitro, cyano, amino, hydroxy, C1-4alkyl, C1-4alkyloxy or trifluoromethyl; R2 is hydrogen; C3- 7alkenyl; C3-7alkynyl, aryl; C3-7cycloalkyl; optionally substituted C1-6alkyl; R3 and R4 each independently are hydrogen, C1-6 alkyl, C3- 7cycloalkyl or aryl; or R3 and R4 taken together form a bivalent radical -R3-R4 of formula (a), (b), (c), (d), or (e), wherein R5a, R5b, R5c R5d each independently are hydrogen, C1-6alkyl or aryl; and aryl is optionally substituted phenyl; as antifungals; their preparation, compositions containing them and their use as a medicine. |
