发明名称 |
PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AND USE THEREOF FOR THE MANUFACTURE OF MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF mGluR5 RECEPTOR MEDIATED DISORDERS |
摘要 |
This invention relates to a compound and the use of the compound of the formula wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4 </SUP>and R<SUP>5 </SUP>are as defined in the description, A signifies -CH-CH- or -C≡C-; and B signifies wherein R<SUP>6 </SUP>to R<SUP>26</SUP>, X and Y are as defined in the specification or a pharmaceutically acceptable salt thereof, for use in pharmaceutical compositions for the treatment or prevention of mGluR5 receptor mediated disorders. |
申请公布号 |
IL155999(A) |
申请公布日期 |
2009.09.01 |
申请号 |
IL20030155999 |
申请日期 |
2003.05.19 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
|
分类号 |
C07D233/64;A61K31/4045;A61K31/415;A61K31/4164;A61K31/4174;A61K31/4178;A61K31/4245;A61K31/437;A61K31/4985;A61P1/08;A61P9/02;A61P9/10;A61P13/02;A61P21/02;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/34;A61P25/36;A61P31/18;A61P43/00;C07D209/14;C07D209/16;C07D231/12;C07D233/54;C07D233/58;C07D233/68;C07D233/90;C07D233/92;C07D233/94;C07D403/06;C07D403/10;C07D413/04;C07D491/147;C07D495/14;C07D498/04;C07D513/14 |
主分类号 |
C07D233/64 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|