发明名称 USE OF EGFR TYROSINE KINASE INHIBITOR FOR PREVENTING BREAST CANCER
摘要 An EGFR tyrosine kinase inhibitor is used in the manufacture of a medicament for use in (a) reducing the trans- formation of epithelial cells from a normal to a malignant state in an invasive breast cancer free human; and/or (b) reducing the transformation of epithelial cells from an intermediate state, between norma l epithelium and malignant invasive epithelium, to a malignant state in an invasive breast cancer free human; and/or (c) causing substantial reversion of epithelial tissue back to a normal state from an intermediate state between normal epithelium and malignant invasive epithelium.
申请公布号 CA2389411(C) 申请公布日期 2009.09.01
申请号 CA20002389411 申请日期 2000.11.01
申请人 THE UNIVERSITY OF MANCHESTER 发明人 BUNDRED, NIGEL JAMES
分类号 A61K31/5377;A61K45/00;A61K31/00;A61K31/138;A61K31/4535;A61K31/517;A61K31/519;A61K31/5355;A61K31/565;A61P35/00;A61P43/00 主分类号 A61K31/5377
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