发明名称 NOVEL HETEROARYL SUBSTITUTED IMIDAZO [1,2 -A] PYRIDINE DERIVATIVES.
摘要 <p>The present invention relates to novel heteroaryl substituted imidazopyridine derivatives, precursors thereof, and therapeutic uses of such compounds, having the structural formula (Ia) and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted imidazopyridine derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measureing clinical efficacy of Alzheimer's disease therapeutic agents.</p>
申请公布号 MX2009007487(A) 申请公布日期 2009.08.31
申请号 MX20090007487 申请日期 2008.01.21
申请人 ASTRAZENECA AB 发明人 JONAS MALMSTROEM;DAVID PYRING;CAN SLIVO;DAVID WENSBO;MICHAELA VALLIN
分类号 A61K31/437;A61K101/00;A61P25/28;C07D471/04 主分类号 A61K31/437
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