| 摘要 |
Disclosed is a process for preparing pteridine and condensed piperazin-2-one derivatives of general formula I (wherein the substituents are disclosed herein), in which a compound of formula II is a) hydrogenated with hydrogen in the presence of a hydrogenation catalyst (selected from the group consisting of rhodium, ruthenium, iridium, platinum, palladium and nickel), and b) a copper, iron or vanadium compound is added, wherein steps a) and b) may take place simultaneously or successively. Also disclosed is an intermediate product of formula III which is obtained after the first step a), and which may optionally be isolated. Additionally, the compound (7R)-2-chloro-7-ethyl-8-isopropyl-7,8-dihydro-5H-pteridin-6-one is further disclosed.
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