| 摘要 |
COMPOSITIONS AND METHODS FOR THE THERAPY OF MALIGNANT DISEASES, SUCH AS LEUKEMIA AND CANCER, ARE DISCLOSED. THE COMPOSITIONS COMPRISE ONE OR MORE OF A WTI POLYNUCLEOTIDE, A WT1 POLYPEPTIDE, AN ANTIGEN-PRESENTING CELL PRESENTING A WTI POLYPEPTIDE, AN ANTIBODY THAT SPECIFICALLY BINDS TO A WT1 POLYPEPTIDE; OR A T CELL THAT SPECIFICALLY REACTS WITH A WT1POLYPEPTIDE. SUCH COMPOSITIONS MAY BE USED, FOR EXAMPLE, FOR THE PREVENTION AND TREATMENT OF METASTATIC DISEASES.
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