ANTIBODIES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME USEFUL FOR INHIBITING ACTIVITY OF METALLOPROTEINS.

摘要

The present invention relates to a compound having the general Formula: (I); wherein: m and n are each independently an integer from 1 to 6; X1-X3 and Y1 -Y3 are each independently O or S; R1-R3 are each independently selected from the group consisting of hydrogen, alkyl, and cycloalkyl; and i R is (CH2)x-C(-O)NR'-(CH2)y-NR'R" whereas: x and y are each independently an integer from 1 to 6; and R' and R" arc each independently selected from the group consisting of, hydrogen, alkyl, and cycloalkyl; and to an antibody comprising an antigen recognition region capable of specifically binding the above compound.