发明名称 AKT protein kinase inhibitors
摘要 Disclosed are compounds of formula A-L-CR, wherein A is a group G-B1-W-(-B2NR13R14)-C(=O)- or G-B1-W-(-B2NR13R14)-CH2-C(=O)- as depicted; CR is a pyrrolopyridine, and L is as defined in the specification. The compounds are AKT protein kinase inhibitors useful for the treatment of hyperproliferative diseases such as cancer.
申请公布号 NZ547327(A) 申请公布日期 2009.08.28
申请号 NZ20040547327 申请日期 2004.11.19
申请人 ARRAY BIOPHARMA INC. 发明人 MITCHELL, IAN S;SPENCER, KEITH L;STENGEL, PETER;HAN, YONGXIN;KALLAN, NICHOLAS C;MUNSON, MARK;VIGERS, GUY P A;BLAKE, JAMES;PISCOPIO, ANTHONY;JOSEY, JOHN;MILLER, SCOTT;XIAO, DENGMING;XU, RIU;RAO, CHANG;WANG, BIN;BERNACKI, APRIL L
分类号 A61K31/496;A61K;A61K31/519;A61K31/53;A61P35/00;C07D253/00;C07D257/12;C07D401/00;C07D471/02 主分类号 A61K31/496
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