PYRAZOLOPYRIDINE DERIVATIVES AS INHIBITORS OF ß-ADRENERGIC RECEPTOR KINASE 1

摘要

PYRAZOLOPYRIDINE DERIVATIVES AS INHIBITORS OF JB-ADRENERGIC RECEPTOR KINASE 1 5 THE INVENTION RELATES TO 6-AMIDO SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVES OF THE FORMULA (1) 0 H N N @RJ N H R3 R2 (1) USEFUL AS INHIBITORS OF BETA-ADRENERGIC RECEPTOR KINASE 1 (BARK-1), COMPOSITIONS 0 CONTAINING SUCH COMPOUNDS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CHRONIC HEART FAILURE, HYPERTENSION, MYOCARDIAL ISCHEMIA AND HEPATITIS C VIRUS (HCV) INFECTIONS, AND FOR THE PREVENTION OF OPIATE ADDICTION. (X0001