| 摘要 |
THE INVENTION RELATES TO A PHARMACEUTICAL COMPOSITION, A THERAPEUTIC COMBINATION PRODUCT AND A KIT COMPRISING A STERICALLY HINDERED PLATINUM COORDINATION COMPOUND AND A NON-PLATINUM BASED ANTI-CANCER AGENT AND A PHARMACEUTICALLY-ACCEPTABLE CARRIER OR DILUENT; TO THE USE THEREOF FOR THE MANUFACTURE OF A MEDICAMENT FOR INHIBITING THE GROWTH OF TUMOUR CELLS IN A HUMAN AFFLICTED THEREWITH WHICH COMPRISES ADMINISTERING TO SUCH HUMAN AN EFFECTIVE TUMOUR CELL GROWTH INHIBITING AMOUNT OF SUCH A THERAPEUTIC COMBINATION PRODUCT OR OF A PHARMACEUTICAL COMPOSITION OF THE INVENTION; IN PARTICULAR WHEN THE STERICALLY HINDERED PLATINUM COORDINATION COMPOUND IS (SP-4-3)-( CIS-AMMINEDICHLORO-[2-METHYLPYRIDINE] PLATINUM (II), OR A PRO-DRUG THEREOF , AND THE NON-PLATINUM BASED ANTI-CANCER AGENT IS SELECTED FROM TAXOL, GEMCITABINE, NAVELBIMNE, DOXIL, 5-FU AND TAXOTERE.
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