发明名称 NANOPARTICLES WITH LIPID CORE AND POLYMER SHELL STRUCTURES FOR PROTEIN DRUG DELIVERY PREPARED BY NANOENCAPSULATION
摘要 The present invention relates to an application of stabilized nanoparticles with a lipid core and shell structures as protein drug carriers, wherein the nanoparticles are prepared by producing nano-sized particles from lecithin obtained from natural soybean, and then adsorbing polaxamer thereon. Here, lecithin is used as an ingredient of core structure, polaxamer is used as an ingredient of shell structure, and both ingredients are applicable to a human body. Thus-obtained nanoparticles having a lipid core and shell structures are applicable in the clinical application. Moreover, said nanoparticles are suitable for use as a drug carrier or a diagnostic agent because they are produced in an aqueous solution without organic solvents.
申请公布号 US2009214633(A1) 申请公布日期 2009.08.27
申请号 US20060296100 申请日期 2006.12.01
申请人 HUNNAM UNIVERSITY INSTITUTE FOR INDUSTRY ACADEMIACOOPERATION 发明人 YUK SOON-HONG;OH KEUN-SANG
分类号 A61K9/127;A61K38/16 主分类号 A61K9/127
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