摘要 |
An oral formulation for mammalian administration and treatment utilizing bioactive pharmaceuticals in need of gastric resistance to promote intestinal absorption. The oral formulation utilizes lower dosages to achieve higher plasma levels and delivers permeable solubilized bioactive pharmaceuticals directly to intestinal mucosa, avoiding premature gastric disintegration. Further, it delivers water and lipid soluble bioactives directly to the intestines overcoming the molecular characteristics previously limiting the therapeutic administration. Upon oral ingestion of the formulation, a disaccharide component is hydrolyzed by intestinal enzymes to bring the bioactive pharmaceutical in contact with the surface of intestinal mucosa. A method of administering oral bioactive pharmaceuticals as well as a method for manufacturing the formulation is disclosed.
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