BIOSENSOR AND A RELATED MANUFACTURING METHOD

摘要

A biosensor platform for a biosensor adapted to detect one or more predetermined target analytes in a sample, the platform comprising a waveguide (202) for transporting, preferably by substantially total internal reflection, light emitted by a light source, at least one light source (204) comprising an organic light emitting diode (OLED), for incoupling light to the waveguide, said light source being arranged on said waveguide, a binding site (214) comprising immobilized bio-recognition material capable of binding to the target analytes, said binding site positioned relative to the waveguide such that evanescent field triggered by the light propagating in the waveguide extend to the binding site, a microfluidic layer (206) comprising one or more microfluidic cavities for conveying the sample past said binding site so as to enable at least part of the target analytes of the sample to bind to the immobilized biorecognition material, wherein said biosensor platform is further configured to enable, when said at least part of the target analytes are bound to the immobilized biorecognition material, fluorescent markers associated with the bound target or other analytes to be excited by the evanescent field so as to emit fluorescence detectable by a detector. The platform may be manufactured using a roll-to-roll technique, for example.