发明名称 |
MENINGOCOCCAL FHBP POLYPEPTIDES |
摘要 |
fHBP is a protein in Neisseria meningitidis. Three families of fHBP are known. To increase the ability of a fHBP protein to elicit antibodies that are cross-reactive between the families, fHBP is selected or engineered to have a sequence which can elicit broad-spectrum bactericidal anti-meningococcal antibodies after administration to a host animal. |
申请公布号 |
CA2716212(A1) |
申请公布日期 |
2009.08.27 |
申请号 |
CA20092716212 |
申请日期 |
2009.02.20 |
申请人 |
NOVARTIS AG |
发明人 |
PIZZA, MARIAGRAZIA;SCARSELLI, MARIA;GIULIANI, MONICA;ARICO, MARIA;RAPPUOLI, RINO |
分类号 |
C07K14/22;A61K39/095 |
主分类号 |
C07K14/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|