发明名称 ISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME
摘要 An isoxazole derivative is provided. The isoxazole derivative has following formula: wherein R1, R2, R3, R4 and R5, independently, include hydrogen, hydroxy or C1-C12 alkoxy optionally substituted with oxirane, thiirane, aziridine, amino, cycloamino, aminohydroxy or cycloaminohydroxy. The invention also provides a pharmaceutical composition for treatment of osteoporosis and cancer including an isoxazole derivative or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.
申请公布号 US2009215768(A1) 申请公布日期 2009.08.27
申请号 US20080243376 申请日期 2008.10.01
申请人 TZENG CHERNG-CHYI;CHEN YEH-LONG;WANG GWO-JAW;HO MAI-LING;CHANG JE-KEN;FU YIN-CHIH 发明人 TZENG CHERNG-CHYI;CHEN YEH-LONG;WANG GWO-JAW;HO MAI-LING;CHANG JE-KEN;FU YIN-CHIH
分类号 A61K31/5377;A61K31/42;A61K31/496;C07D261/06;C07D413/02;C07D413/12 主分类号 A61K31/5377
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