发明名称 NITROGEN-CONTAINING BYCYCLIC COMPOUNDS ACTIVE ON CHRONIC PAIN CONDITIONS
摘要 The invention refers to compounds of general formula (I) wherein the R groups are, independently, H, C1-6alkyl, aryl, CF3; Y is CH2, C=O; X is bond, C=O, SO2, or C=N-CN; m is 0, 1; n is 0, 1; A is a heterocycle, or a phenyl group optionally substituted as defined in the specification. The compounds are active on chronic pain conditions of different origin; they can be administered alone or with other drugs. Most of these compounds are new. The invention include a process to prepare said compounds, and pharmaceutical compositions suitable for their administration to a patient.
申请公布号 CA2716230(A1) 申请公布日期 2009.08.27
申请号 CA20092716230 申请日期 2009.02.17
申请人 NEUROTUNE AG 发明人 GHELARDINI, CARLA;MARTINELLI, MARISA;PARINI, CARLO;RONZONI, SILVANO
分类号 C07D487/04;A61K31/4985;A61P25/00;A61P29/00 主分类号 C07D487/04
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