| 摘要 |
A method for preparing highly stable aqueous gels based on metronidazole, well suited for treating such skin conditions as rosacea, acne and dermatitis, entails the successive steps of: (A) forming a solvent medium M comprising water and propylene glycol; (B) dissolving the metronidazole in this solvent medium M, and optionally diluting the medium obtained by addition of water, whereby a solution S of metronidazole is obtained; and thence (C) mixing the solution S obtained with a gelling polymer, in a sufficient amount to ensure gelling of the composition.
|
