Optimized Fc Variants and methods for their generation
摘要
The present invention relates to Fc variants having increased affinity for FcgammaRIIc, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.
申请公布号
US2009215991(A1)
申请公布日期
2009.08.27
申请号
US20070841755
申请日期
2007.08.20
申请人
XENCOR, INC.
发明人
LAZAR GREGORY ALAN;DANG WEI;DESJARLAIS JOHN R.;KARKI SHER BAHADUR;VAFA OMID;HAYES ROBERT
