SUBSTRATE FOR ASSAYING ?-GLUCAN AND/OR ENDOTOXIN AND ASSAY METHOD

摘要

Disclosed are a peptide derivative for assaying ß-glucan or an endotoxin which enables a highly sensitive assay and a method of assaying ß-glucan and/or an endotoxin using the same. (1) A peptide derivative represented by general formula [1]: X-A1-Gly-Arg-A2-E-D [1]; (2) a reagent for assaying ß-glucan and/or an endotoxin which contains the peptide derivative as described above; (3) a method of assaying ß-glucan and/or an endotoxin characterized by comprising reacting a sample containing ß-glucan and/or the endotoxin with limulus blood cell components and the above-described peptide derivative, separating and quantifying the unreacted substance represented by general formula [2] that has been released consequently: H-A2-E-D [2] and then conducting the assay based on the data; and (4) a reagent kit for assaying ß-glucan and/or an endotoxin which contains limulus blood cell components and the above-described peptide derivative as the constituents of the same.