发明名称 CRISTALLINES, ENANTIOMERICALLY PURE SALT FORM OF A BETA-AGONIST, AND THE USE THEREOF AS A DRUG
摘要 The invention relates to a crystalline, enantiomerically pure hydrochloride salt of N-(5-{2-[3-(4,4-diethyl-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-2-hydroxy-phenyl)-methane sulfonamide, preferably N-(5-{(R)-2-[3-(4,4-diethyl-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy- ethyl}-2-hydroxy-phenyl)-methane sulfonamide, and the effect thereof as a long-term betamimetic agent, alone or combined with at least one other active ingredient, in the treatment of respiratory diseases.
申请公布号 CA2712706(A1) 申请公布日期 2009.08.27
申请号 CA20092712706 申请日期 2009.02.17
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 WERTHMANN, ULRIKE;SANTAGOSTINO, MARCO;DURAN, ADIL
分类号 C07D265/18;A61P11/00 主分类号 C07D265/18
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