摘要 |
PROBLEM TO BE SOLVED: To provide an ultrafine dry powder composition having characteristics particularly suitable for pulmonary delivery for therapeutic and other purposes. SOLUTION: The process for preparing ultrafine powders of biological macromolecules comprises atomizing liquid solutions of the macromolecules, drying the droplets formed in the atomization step, and collecting the particles which result from drying. Properly controlling each of the atomization, drying, and collection steps enables the preparation of an ultrafine dry powder composition having characteristics particularly suitable for pulmonary delivery for therapeutic and other purposes. COPYRIGHT: (C)2009,JPO&INPIT |