发明名称 PROCESS FOR PRODUCTION OF CRYSTAL OF PURINE NUCLEOSIDE COMPOUND
摘要 Disclosed is a process for producing a crystal of a purine nucleoside compound, particularly a crystal of 2',3'-dideoxyinosine, which is not decomposed during storage and has excellent storage stability. Specifically disclosed is a process for producing a crystal of a purine nucleoside which has a concentration of phosphate attached to the crystal of 25 ppm or more and has excellent storage stability. The process comprises the steps of: (1) preparing an aqueous solution containing a phosphate ion (PO43-) and a purine nucleoside compound; and (2) crystallizing out the purine nucleoside compound from the aqueous solution. ® KIPO & WIPO 2009
申请公布号 KR20090091237(A) 申请公布日期 2009.08.26
申请号 KR20097015013 申请日期 2007.12.26
申请人 AJINOMOTO CO., INC. 发明人 NAITO MASAKI;KIMURA YOSHITOMO;UEDA HIROYA;HARADA MINORU
分类号 C07D473/30;C07H19/167;C07H19/173 主分类号 C07D473/30
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