发明名称 |
SPARC-DERIVED CANCER REJECTION ANTIGEN PEPTIDE AND PHARMACEUTICAL COMPRISING THE SAME |
摘要 |
<p>It is an objective of the present invention to identify SPARC protein-derived peptides that are able to induce human killer T cells and helper T cells having cytotoxic activity to tumors, and to provide a means for carrying out a tumor immunotherapy of patients with various types of cancers overexpressing SPARC. The present invention provides a peptide of any of the following:
(A) a peptide which consists of the amino acid sequence as shown in any one of SEQ ID NOS: 1 to 3; or
(B) a peptide which consists of an amino acid sequence comprising a substitution or addition of one or several amino acids with respect to the peptide consisting of the amino acid sequence as shown in any one of SEQ ID NOS: 1 to 3, and which has capacity to induce cytotoxic (killer) T cells.</p> |
申请公布号 |
EP2030984(A4) |
申请公布日期 |
2009.08.26 |
申请号 |
EP20070745372 |
申请日期 |
2007.06.15 |
申请人 |
ONCO THERAPY SCIENCE, INC. |
发明人 |
NISHIMURA, YASUHARU;IKUTA, YOSHIAKI;NAKATSURU, SHUICHI |
分类号 |
C07K14/47;A61K38/00;A61K39/00;A61P35/00;C07K16/18;C12N5/06 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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