发明名称 Terphenyl derivatives for treatment of alzheimer's disease
摘要 The present invention relates to compounds having the general formula (I) with the definitions of X, Y, R 1 -R 4 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of ³-secretase activity.
申请公布号 ZA200809857(B) 申请公布日期 2009.08.26
申请号 ZA20080009857 申请日期 2008.11.19
申请人 ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC.;CELLZOME LIMITED 发明人 WILSON, FRANCIS;READER, VALERIE;HARRISON, RICHARD, JOHN;SUNOSE, MIHIRO;MAJOR, JEREMY;BOUSSARD, CYRILLE;TAYLOR, JESS;CANSFIELD, ANDREW;BURCKHARDT, SVENJA;JONES, ALISON;BELL, KATHRYN;MOREL, ADELINE;HERNADEZ-PERNI, REMEDIOS;HO, CHIH YUNG
分类号 A61K;A61P;C07C;C07D 主分类号 A61K
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