发明名称 |
Quinoxalinyl macrocyclic hepatitus C virus serine protease inhibitors |
摘要 |
The present invention relates to compounds, including compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. |
申请公布号 |
ZA200810519(B) |
申请公布日期 |
2009.08.26 |
申请号 |
ZA20080010519 |
申请日期 |
2008.12.11 |
申请人 |
ENANTA PHARMACEUTICALS, INC. |
发明人 |
OR, YAT SUN;MOORE, JOEL D.;LIU, DONG;SUN, YING;GAI, YONGHUA;DATONG TANG;NIU, DEQIANG;XU, GUOYOU;WANG, ZHE |
分类号 |
A61K |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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