ANTIMICROBIAL AGENT

摘要

#CMT# #/CMT# Use of an inorganic material to form a hydrogen cation, when contacted with an aqueous medium, for the achievement of antimicrobial effect. #CMT#ACTIVITY : #/CMT# Antimicrobial. #CMT#MECHANISM OF ACTION : #/CMT# None given. #CMT#USE : #/CMT# The inorganic material is useful to form a hydrogen cation for the achievement of antimicrobial effect. The material is used as an additive material for hygienic absorbent articles or wound coverings, where the polymer contains fibers or - lattice on its surface in which the material is separated. The material is used as an additive for varnish, coating or adhesive, where the amount of material in varnish, coating or adhesive is 0.01-70 vol.%. The material is used as an additive for a body caring agent, furniture pieces, a product (such as a switch, armature, credit card, keyboard, mobile phone housing, coin, bills, door buckle or a part of an interior equipment of a public transportation) that is frequently used by living being, filter or clothing article, where the polymer fibers contain the separated material on their surface. The material is used as an additive for implants such as catheter, coronary stent from nitinol that is coated with the material, bone implant, tooth implant, container prosthesis or endoprosthesis, where the catheter is a port catheter comprising a cup with silicon membrane and a connected tube, where cup from a polymer material or with a polymer material forms a covering material containing the material and equipped at least partially with a layer; and the material contains polymer material and/or silicon membrane (all claimed). No biological data given. #CMT#ADVANTAGE : #/CMT# The material is economic and biocompatible. The material is slightly cytotoxic and exhibits slight thrombogenetic effect, compared to the existing material. #CMT#INORGANIC CHEMISTRY : #/CMT# Preferred Components: The hydrogen-cation is H 3O +>, H 5O 2 +> and/or H 9O 4 +>. The aqueous medium is water, solution, suspension, body fluid or tissue fluid. The aqueous medium exists in the form of an adsorbed moisture film on the material surface. The pH value of the aqueous medium is less than 6 (preferably less than 5), through the development of hydrogen cation. The material is soluble in 0.1 mol/l of the aqueous medium. The material contains molybdenum and/or tungsten. The surface of the material is partially oxidized. The material is molybdenum-oxide such as MoO 2 and/or MoO 3, molybdenum material or its alloy and/or molybdenum compound, where the surface exibits molybdenum oxide layers. The molybdenum alloy is 0.1 wt.% of molybdenum to 1 wt.% of lanthanum oxide, 0.5 wt.% of molybdenum, 0.08 wt.% of titanium, 0.01 wt.% of zirconium to 0.04 wt.% of carbon, 5 wt.% of molybdenum to 50 wt.% of rhenium or 1.2 wt.% of molybdenum, 0.02 wt.% of hafnium to 0.15 wt.% of carbon. The molybdenum compound is molybdenum carbide, molybdenum nitride, molybdenum silicide and/or molybdenum sulfide. The molybdenum- or tungsten oxide or layered molybdenum- or tungsten oxide reacts with water to form molybdenum acid, which reacts with water to form H 3O +>, MoO 4 -> or WO 4 -> and/or MoO 4 2> -> or WO 4 2> ->. The material is tungsten-oxide such as blue oxide and/or tungsten trioxide. The material is tungsten material or tungsten alloy and/or tungsten compound, where the surface exhibits a tungsten oxide layer. The tungsten alloy is 0.1 wt.% of tungsten to 1 wt.% of lanthanum oxide or 1 wt.% of tungsten to 26 wt.% of rhenium. The tungsten compound is tungsten carbide, tungsten nitride, tungsten silicide and/or tungsten sulfide. The medium further comprises a phase that is chemically nobler than the material. The material is in the form of molybdenum-silver, molybdenum-copper, molybdenum-tin, tungsten-silver, tungsten-copper and/or tungsten-tin. The amount of molybdenum and/or tungsten is 10-90 wt.%. The material is denser or porous. The material exists as a layer or its component. The layer is molybdenum or molybdenum-oxide and/or tungsten or tungsten-oxide. The layer is separated through electron ray evaporation, sputtering, chemical steam separation, electrophoresis, slurry-technology, solgel-technology or plasma injection. The layer is spongy or porous structure with a pore size of 50-900 mu m. The material in the layer exists in the form of insulator, preferably non-related agglomerates. The average size of the single material agglomerate is less than 5 mu m. The material agglomerate is formed by applying a sludge or by separating from gas phase and more optionally subsequently annealed. The material exists in association with one or more materials as composites. The amount of the material is 0.1-50 vol.%. The composite material exhibits a polymer matrix. The polymer matrix is a highly crosslinked polyethylene. The composite material is produced by injection molding using an extruder compound granulate. The composite material is alumina-molybdenum trioxide, alumina-tungsten trioxide, zirconium oxide-molybdenum trioxide, zirconium oxide-tungsten trioxide, alumina-molybdenum-molybdenum trioxide, alumina-tungsten-tungsten trioxide, zirconium oxide-molybdenum-molybdenum trioxide, zirconium oxide-tungsten-tungsten trioxide, titanium oxide-molybdenum trioxide, titanium oxide-tungsten trioxide, titanium oxide-molybdenum-molybdenum trioxide, titanium oxide-tungsten-tungsten trioxide, silicon dioxide-molybdenum trioxide, silicon dioxide-molybdenum-molybdenum trioxide or silicon dioxide-tungsten-tungsten trioxide. The amount of molybdenum trioxide or tungsten trioxide is 0.001-50 mol.%. The molar ratio of zirconium oxide, alumina, titanium oxide or silicon dioxide to molybdenum trioxide or tungsten trioxide is 1:100.