发明名称 |
Oligonucleotides or their functional homologues, a composition comprising the same and a method of treating B cell neoplasm |
摘要 |
The invention provides nine oligonucleotides with sequences of SEQ ID NO: 1-9 or their functional homologues or a composition comprising the same and a method for treating B cell neoplasm by using the oligonucleotides or their functional homologues or the composition comprising the oligonucleotides. The oligonucleotides induce the apoptosis of B cell neoplastic cells, up-regulate CD40 on B cell neoplastic cells and stimulate the production of IL-10 from B cell neoplastic cells. |
申请公布号 |
ZA200710311(B) |
申请公布日期 |
2009.08.26 |
申请号 |
ZA20070010311 |
申请日期 |
2006.02.13 |
申请人 |
CHANGCHUN HUAPU BIOTECHNOLOGY CO. LTD. |
发明人 |
WANG, LI-YING;BAO, MU-SHENG;YU, YONG-LI |
分类号 |
A61K;A61P;C07H;C12N15/117 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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