发明名称 |
ENABLING METHODS TO IDENTIFY ALLOSTERIC MODULATORS OF RECEPTOR ACTIVITY |
摘要 |
A method developed to identify receptor modulators, involving providing a mutant receptor, wherein said mutant receptor has a mutation that alters the activity of said mutant receptor compared to a wild type receptor; contacting said mutant receptor with a candidate compound; and determining whether said candidate compound modulates the activity of said mutant receptor.
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申请公布号 |
US2009209525(A1) |
申请公布日期 |
2009.08.20 |
申请号 |
US20080340393 |
申请日期 |
2008.12.19 |
申请人 |
SPALDING TRACY A;BRANN MARK R;DAVIS ROBERT E;BURSTEIN ETHAN S |
发明人 |
SPALDING TRACY A;BRANN MARK R.;DAVIS ROBERT E.;BURSTEIN ETHAN S. |
分类号 |
A61K31/551;A61K31/195;A61K31/4025;A61K31/4439;A61K31/445;A61K31/46;A61K31/538;C12Q1/68;G01N33/53 |
主分类号 |
A61K31/551 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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