摘要 |
<p>Disclosed is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof, which has an excellent inhibitory activity on a sodium channel and is therefore useful as a therapeutic agent for various types of neuralgia, nervous disorders, epilepsy, insomnia, premature ejaculation and others or as an analgesic agent. (I) wherein Q represents an ethylene or the like; R1, R2 and R3 independently represent a hydrogen or the like; X1 represents a C1-6 alkylene or the like; X2 represents a C1-6 alkylene or the like; A1 represent a 5- to 6-membered heterocyclic group or the like; and A2 represents a C6-14 aryl or the like.</p> |
申请人 |
EISAI R & D MANAGEMENT CO., LTD.;OZAKI, FUMIHIRO;SOEJIMA, MOTOHIRO;ISHIDA, TASUKU;NORIMINE, YOSHIHIKO;KURUSU, NOBUYUKI;DOI, ERIKO;KANEKO, TOSHIHIKO;HASEGAWA, DAIJU;KOBAYASHI, KIYOAKI;YAMAMOTO, NOBORU |
发明人 |
OZAKI, FUMIHIRO;SOEJIMA, MOTOHIRO;ISHIDA, TASUKU;NORIMINE, YOSHIHIKO;KURUSU, NOBUYUKI;DOI, ERIKO;KANEKO, TOSHIHIKO;HASEGAWA, DAIJU;KOBAYASHI, KIYOAKI;YAMAMOTO, NOBORU |