发明名称 NOVEL AMPHYL DERIVATIVES OF ALFA-C-PHENYL-N-TRET-BUTYLNITRONE
摘要 FIELD: chemistry. ^ SUBSTANCE: claimed invention relates to derivatives of -C-phenyl-N-Tret-butylnitrone of general formula (I) , where X represents lactobionamide group, quarternary ammonium group or group ; m represents 1, 2 or 3; y represents 0 or 1; Y represents group -CH2-; m' represents 1; X' represents alkyl chain C4-C14, if necessary substituted with one or several fluorine atoms; Y' represents group selected from functional amide group (-NHC(O)-), urethane group (-OC(O)NH-) or thioester bridge (-S-). ^ EFFECT: invention also relates to application of claimed compounds for obtaining medication for treatment of pathologies induced by oxidative stress and formation of compounds with free oxygen radicals and to application of formula (I) compounds for obtaining cosmetic composition for prevention and treatment of ageing effects. ^ 9 cl, 4 tbl, 11 dwg
申请公布号 RU2364602(C2) 申请公布日期 2009.08.20
申请号 RU20050117618 申请日期 2003.11.07
申请人 TS FARMA;JUNIVERSITE D`AVIN'ON EH DE PEI DJU VOKLJUZ 发明人 DJURAN GREGORI;POLIDORI ANZH;PUCHCHI BERNAR
分类号 A61K8/60;A61K31/15;A61K31/7016;A61P9/10;A61P17/16;A61P25/00;A61P25/14;A61P25/28;A61P35/00;A61P39/06;A61Q19/00;A61Q19/08;C07C323/03;C07H3/04;C07H5/06;C07H15/18;E04H4/00;E04H4/04 主分类号 A61K8/60
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