发明名称 |
INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 |
摘要 |
This invention relates to novel compounds of the Formula (I), any of the formulas I1-I26 la1-3-lj1-3 or pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11ß-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of cortisol in a cell or the inhibition of the conversion of cortisone to cortisol in a cell.
|
申请公布号 |
CA2715290(A1) |
申请公布日期 |
2009.08.20 |
申请号 |
CA20092715290 |
申请日期 |
2009.02.13 |
申请人 |
VITAE PHARMACEUTICALS, INC. |
发明人 |
CLAREMON, DAVID A.;ZHUANG, LINGHANG;YE, YUANJIE;SINGH, SURESH B.;TICE, COLIN M.;SIMPSON, ROBERT D. |
分类号 |
C07D243/04;A61P3/04;C07D211/76;C07D265/10 |
主分类号 |
C07D243/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|