The likelihood that a compound will exhibit bone marrow toxicity in an in vivo assay predicted by the ability of the compound to inhibit at least eight kinases from a selected group.
申请公布号
CA2714183(A1)
申请公布日期
2009.08.20
申请号
CA20092714183
申请日期
2009.02.06
申请人
F. HOFFMANN-LA ROCHE AG
发明人
BITTER, HANS MARCUS LUDWIG;GOLDSTEIN, DAVID MICHAEL;KOLAJA, KYLE L.;LIN, HENRY;OLAHARSKI, ANDREW JAMES;UPPAL, HIRDESH