发明名称 SUBSTITUTED PIPERIDINES CONTAINING A HETEROARYLAMIDE OR HETEROARYLPHENYL MOIETY.
摘要 <p>The invention provides compounds of the formula (I) having PKA and PKB kinase inhibiting compounds of the formula (I): GP 1 J T 2 J N 4 R N H (I) or salts, solvates, tautomers or N-oxides thereof, wherein (1) GP is a group GP1: HET 2a a Q G (HNCO)f 7 (R )x N * (GP1) (2) GP is a group GP2: 10 (R )r O 2a a QG (CH2)w N V H N * (GP2) wherein HET is a monocyclic or bicyclic heterocyclic group containing up to 4 heteroatom ring members; the ring V is a monocyclic or bicyclic heteroaryl group of 5 to 10 ring members; and J1, J2, R4, R7, R10, Q2a, Ga, x, w and f are as defined in the claims.</p>
申请公布号 MX2009006650(A) 申请公布日期 2009.08.20
申请号 MX20090006650 申请日期 2007.12.20
申请人 ASTEX THERAPEUTICS LIMITED 发明人 RICHARD WILLIAM ARTHUR LUKE;MARINUS LEENDERT VERDONK;STEVEN JOHN WOODHEAD;HANNAH FIONA SORE;DAVID WINTER WALKER;IAN COLLINS;ZBIGNIEW STANLEY MATUSIAK;CHRISTOPHER HAMLETT;TATIANA FARIA DA FONSECA MCHARDY;GREGORY RICHARD CARR;JEFFREY JAMES MORRIS;KWAI MING CHEUNG
分类号 C07D487/04;A61K31/519;A61P35/00;C07D471/04;C07D473/34 主分类号 C07D487/04
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