发明名称 METHOD OF PREVENTION AND CORRECTION OF TOXIC IMMUNE ALTERATIONS
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, namely to occupational diseases, and can be used for correction of immune alterations in persons being in contact with toxic substances. The method is carried out as follows. Introduction of immunostimulant Cyclopheron is preceded with individual adverse effect test by incubation in vitro of Cyclopheron and mononuclear cells separated from peripheral blood. Cyclopheron is introduced provided CD19+ B-lymphocyte count is exceeded by 20% and more, and activated HLA-DR+ lymphocyte count by 15% and more. ^ EFFECT: method allows improving effectiveness of correction of immune alterations owing to prediction of body's immune response to Cyclopheron therapy. ^ 1 tbl, 5 ex
申请公布号 RU2364396(C2) 申请公布日期 2009.08.20
申请号 RU20070141453 申请日期 2007.11.07
申请人 FGUN "NIZHEGORODSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT GIGIENY I PROFESSIONAL'NOJ PATOLOGII" ROSPOTREBNADZORA 发明人 LITOVSKAJA ANNA VLADIMIROVNA;SHMAKOVA TAT'JANA VIKTOROVNA;PUZATKINA OL'GA VIKTOROVNA
分类号 A61K31/21;A61P37/02;G01N33/48 主分类号 A61K31/21
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