发明名称 |
SELECTIVE AGONIST OF TOLL-LIKE RECEPTOR 3 |
摘要 |
A mismatched double-stranded ribonucleic acid, which is an agonist for Toll-like receptor 3 (TLR3), is used in vitro or in vivo as an antimicrobial agent, antiproliferative agent, and/or immunostimulant. Poly(l:C11-14U) is a more selective agonist of TLR3 as compared to poly(l:C) even though the both double-stranded RNA are structurally analogous.
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申请公布号 |
CA2715293(A1) |
申请公布日期 |
2009.08.20 |
申请号 |
CA20092715293 |
申请日期 |
2009.02.17 |
申请人 |
HEMISPHERX BIOPHARMA, INC. |
发明人 |
CARTER, WILLIAM A.;STRAYER, DAVID |
分类号 |
A61K31/7105;A61P35/00;A61P37/02;C12N15/11 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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