| 摘要 |
[Problems] To provide a process by which non-discolored, shape-stable microneedles and microneedle arrays can be produced without impairing the sharpness of needle points in molding and while protecting the molecular weight from decrease due to hydrolysis, and products made by the process. [Means for Solving Problems] A process for the production of microneedles which comprises the feeding step of feeding a resin fluid to a mold provided with needle forming sections having an opening diameter of 50 to 200 µm and a depth of 100 to 450 µm, the filling step of filling the resin fluid into the needle-forming sections, and the solidification step of solidifying the filled resin fluid by cooling, characterized in that the feeding, filling and solidification steps are conducted under a reduced pressure or vacuum. |
