| 摘要 |
<p>A fusion antigen used as a vaccine. The fusion antigen contains a ligand moiety, a Pseudomonas exotoxin A translocation domain II, an antigenic moiety, and a carboxyl terminal moiety. The ligand moiety reacts, recognizes or binds to receptors on a target cell. The carboxyl terminal moiety contains a polypeptide having a sequence KDEL. The antigenic moiety is derived from a pathogen selected from the group consisting of PRRSV, equine arteritis virus, circovirus type II, human immunodeficiency virus, lactate dehydrogenase elevating virus, and simian hemorrhagic fever virus. Pharmaceutical compositions and methods of inducing an immune response using the same are also disclosed.
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