发明名称 |
METHOD FOR PRODUCTION OF HUMAN ERYTHROPOIETIN |
摘要 |
<p>Disclosed is a method for production of human erythropoietin. By the method, the cells are cultured in a serum-free medium with repetitive medium exchanges, in which medium exchange is carried out either by collecting 80 to 95% of the culture when viable cell density has reached at 2×106˜4×106 cells/mL, or by adjusting the amount of the exchanged medium so that the initial density of the viable cells may be 1.5×105˜2.5×105 cells/mL.</p> |
申请公布号 |
EP2089424(A1) |
申请公布日期 |
2009.08.19 |
申请号 |
EP20060843366 |
申请日期 |
2006.12.19 |
申请人 |
JCR PHARMACEUTICALS CO., LTD. |
发明人 |
KAWASAKI, ATSUKO;MUKAI, KEISUKE;KIRIHARA, SEI |
分类号 |
C07K14/505 |
主分类号 |
C07K14/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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